Topic

Cancer Treatment Biology

Explore the research, concepts, and evidence that shape understanding of cancer treatment biology and its relevance to cancer.

Related Cancer Types

Breast Cancer Brain & Central Nervous System Cancer Lymphoma

Related Concepts

Tumor Microenvironment TP53 MYC Apoptosis T Cells Glycolysis

Topic

Related Research

Long-Lasting Complete Intracranial Response to Trastuzumab Deruxtecan in HER2-Positive Breast Cancer

A patient with HER2-positive breast cancer and more than 20 active brain metastases achieved a complete intracranial response to trastuzumab deruxtecan after progressing on WBRT and T-DM1, maintained for over 20 months.

CD19 CAR-T Therapy Produces Durable Remission in TP53-Mutated, Triple-Refractory Burkitt Lymphoma

A 16-year-old male with TP53-mutated Burkitt lymphoma, initially misdiagnosed and refractory to three chemotherapy regimens, achieved complete metabolic response and remains in remission 30 months after CD19-directed CAR-T cell therapy (axicabtagene ciloleucel).